The original Ghost in the Shell manga by Masamune Shirow and the film by Mamoru Oshii proved to be as iconic as Blade Runner, and truly defined the cyberpunk genre in the anime world. Even so, the later Stand-Alone Complex television series far outdid the originals in getting cyberpunk right.
Not only by avoiding the stale "robots are taking over!" meme that Hollywood writers can't get past. But in imagining a technological society just short of the "Singularity" (one of those evolutionary steps that will always be just over the horizon), and yet no more or less dystopian than this one.
The human species keeps muddling through, as it always has and always will.
The series is being rebooted in a four-film series featuring a new cast, designs, director and writer (though still produced by Production I.G.). It's a prequel even to Stand-Alone Complex, taking Kusanagi back to the beginning of her career with Section 9. This is a series I definitely want to see.